Settings
The handicap settings are controlled at the time that each game is created. The settings range from 100 percent -- no handicap -- to 50 percent, a full handicap. Each player is able to set his own handicap level in the game lobby via a drop-down menu on the right-side of the screen. By default, each player is set to no handicap.
Buildings
Buildings are affected by the handicap settings only in their available hit points. A handicap setting of 50 percent will reduce a building's hit points by half. The build time, cost, and production abilities of buildings are unaffected by handicap settings.
Units
Units are the game objects most affected by handicap, since unit health is a very important and finely-tuned aspect of the game. Units have their health affected, but as with buildings, cost and abilities are unaffected. Handicap settings do not affect how much damage is done, either.
Technologies
Technologies, having no health, are the least affected game object. The speed with which technologies change is important to a consistent game experience, and is as such not affected by handicap settings. If technologies were slowed by handicap, many game strategies would be unplayable.