Darkwatch
Play as Jericho Cross in Darkwatch, a vampire-themed first-person shooter. Jericho, a bandit, is killed and turned into a vampire while robbing a train one night. Left for dead by the powerful vampire that turned him, he is rescued by another vampire, a young lady who is a member of Darkwatch. Players will go through varying campaigns and levels to track down Jericho's vampire killer and defeat him.
Legacy of Kain: Defiance
Play as the vicious vampire, Kain, and the moody demon, Raziel, as they struggle to fulfill their mutual destinies. Immortality doesn't mean the job will be easy, though. Plenty of demons and monsters block the way to their goals. Fight back by siphoning their blood as Kain, or devour their souls when playing as Raziel.
Vampire Night
Go vampire slaying in this arcade style, PS2 Light-Gun supported game. Players point their gun at the screen and blast away werewolves, monsters and of course, vampires. There are humans to save along the way, too---but save them before the monsters make a meal out of them. Special missions are included along with the standard game, offering rewards like better weaponry once completed.
Van Helsing
Travel through Transylvanian villages and castles to track down Van Helsing's greatest foe, Dracula. Fight classic monsters along the way, such as Frankenstein, Igor, the Wolf Man and Mr. Hyde. Upgrade your clever armory of gadgets as you go to make sure no monster will get the best of you.
Buffy the Vampire Slayer: Chaos Bleeds
Fans of the television show will enjoy Buffy's foray into the video game world. Play as Buffy and her fellow vampire slayers, including Spike, Xander and Willow, as they struggle against an impending vampire onslaught. Use weapons like holy water, an ax, a shovel and a wooden stake to decimate Buffy's foes.