Weapons
Unlocking the Grenade allows you to toss a high-explosive grenade to destroy multiple Gloopies at once. But be careful. Standing too close to the explosion can kill you, as well. The Box Gun reward allows you to position a gun on the ground that then spins and shoots 30 rounds at Gloopies. Keep your distance so you don't get hit. Another weapon reward, the Saw Drone, extends blades and spins around in search of Gloopies to destroy. The Saw Drone will never attack you. You must kill the Razor Queen with your sword to unlock the Razor Glaive reward, which is a knife crafted from the Razor Queen's own claws. While powerful enough to kill most foes with one swing, the Razor Glaive brings with it extra weight, slowing your movement.
Diversions
Unlock the Lure reward if you need to create a diversion. Lure allows you to toss a gas grenade that releases a red mist of pheromones, drawing the Gloopies' attention. Once distracted, the Gloopies become easy targets. The Inhibitor disrupts the Gloopies' ability to communicate. As a result, the Gloopies won't be able to coordinate an assault, effectively reducing the number of attackers.
Movement
The Sprint reward allows you to run faster, helping you avoid Gloopies and other potential hazards. However, each time you sprint, the effort leaves you exhausted. You won't be able to move or swing your knife until you recover. The Teleporter reward teleports you from one spot to another. Wherever you plant the device is where you will teleport to upon activation.
Protection
Wearing the Hazard Suit protects you from fire, ice, lava and even sticky goo for a brief amount of time. Another reward, the Reactive Armor, explodes during normally fatal impacts, killing your surrounding enemies and leaving you unharmed. In essence, the Reactive Armor acts as an extra life. The Repulsor reward also offers protection, creating a bubble of compression waves to repel Gloopies and to provide you a chance to regroup. Finally, the Instant Wall reward lets you erect a wall wherever you want, creating a protective barrier between you and the Gloopies.