Purpose
As an introduction to the story itself, the purpose of a prologue is to usher in the plot of the book and acquaint the readers with its characters. Its intent is to familiarize the audience with the story that is about to be told. A preface doesn't talk about the story, but introduces the idea and concept of the book to its readers. The author's intent is to inform the audience of the ideology behind the book, give thanks and convey any personal messages.
Voice
The prologue is tied to the main story and is written from the perspective of the narrator or a character of the book. It is in the voice of the story. The preface is always a message from the author, providing a platform for her to communicate with the readers.
Content
Prologues typically contain background information on the story, including where the story is set and any preliminary information needed to understand the plot. Narrated as part of the story itself, it may be set in a time period prior to that when the actual story is taking place. Prefaces cover what the author wants to say, including acknowledgements to involved parties, credits and dedications. The conceptualization of the book and how ideas were generated are also explained here.
Change Over Time
Prefaces can be added and edited after a book has been published. Newer editions might have new prefaces, with the author addressing different issues and presenting changes from the earlier edition. Prologues, however, are consistent. Written as part of the original story, they are not edited to reflect changing viewpoints.
Occurrence
Prologues occur exclusively in works of fiction. As a prelude to the story, their occurrence is limited to publications where there is a story to be told. Reference books and works of research do not have the scope for prologues. Prefaces have no such limitations and occur in both fiction and non-fiction books. Research papers and reference books typically use the preface as a platform to give credits to sources and acknowledge collaborative parties. Choice of research ideas are also explained in the preface.