Eccentricity
The planets of the solar system all have nearly circular orbits, but Pluto travels around the sun in an elliptical (egg-shaped) path. This is known as an eccentric orbit.
Inclination
The orbits of the planets lie close to a level plane, called the ecliptic. Pluto orbits on a different plane, one that is inclined 17 degrees from the ecliptic.
Sometimes Closer than Neptune
When making its closest approach to the sun (perihelion) during its 248-year orbit, Pluto is within the orbit of Neptune.
Resonance with Neptune
Pluto's orbit is in a 3:2 resonance with Neptune's. The two planets' gravitational fields affect each other such that Pluto's orbit takes exactly 1.5 times that of Neptune.
Kuiper Belt
Pluto's orbit passes through the Kuiper Belt, a region of small icy bodies found beyond the orbit of the planets.