Larvae and Eggs
There are few confirmed predators of Karner blue larvae and eggs. Spined soldier bugs, paper wasps and some ants have been seen removing larvae, while the seven-spotted lady beetle has been confirmed to prey on them. Other insects are suspected but not confirmed.
Adults
Spiders, robber flies, ambush bugs and dragonflies prey on adult Karner blues. Assassin bugs are suspected but not confirmed.
Parasitoids
Parasitoids, or parasites that kill their hosts, also prey on the Karner blue. Main parasitoids include braconid and ichneumoid wasps as well as tachinid flies.
Vertebrates
It is possible that birds prey on Karner blues. White-tailed deer also have been seen eating eggs, larvae and pupae, although this may be unintentional consumption as the deer grazes.
Defense
As no intentional vertebrate predators have been confirmed, it is possible the Karner blue butterflies have some smell, taste, or toxin that serves as a defense against predators.