Super Mario World
Super Mario World was the game that was packaged with the Super Nintendo when it was first released in 1991 (1990 in Japan). It is considered by some to be the best entry in the Super Mario franchise.
Starfox
Starfox is more than a great space shooter; it was a milestone for video games. It is widely considered to be the first truly 3D video game ever released on a home console.
Super Metroid
Super Metroid, the SNES sequel/remake to Metroid, has been referred to as the single best SNES game ever released, by such gaming publications as "IGN" and "GameSpot."
Super Star Wars Trilogy
If you are a fan of Star Wars or just enjoy an absurdly difficult video game, the Super Star Wars Trilogy is an excellent time sink for a weekend or two.
Shaq Fu
While the previous games listed are considered to be some of the Super Nintendo's best, Shaq Fu is considered to be far and away the worst. It is worth playing just to say you have experienced it first-hand.