Minimum System Requirements
BioShock was released in 2007, so most computers nowadays should meet the minimum system requirements without any trouble. If you are using an older computer, however, you need to make sure that your computer has what it takes to run BioShock at all. You need a single-core 2.4 gigahertz processor, 1GB of RAM, a DirectX 9 video card with 128MB of RAM, a DirectX 9̵1;compatible sound card and 8GB of hard drive space. Any computer with specifications higher than this is able to run BioShock without any trouble.
Video Drivers and DirectX
Out-of-date video drivers are a common cause for computer game errors. Since applications such as Internet browsers and word processors don't need a lot of graphics support, many computer users don't think to check for driver updates on a regular basis. Find out what kind of video card is installed within your computer, then visit the manufacturer's website to see if any updates have been released. You should also make sure that your installed version of DirectX is up to date.
Graphics Settings
If you have just the minimum system requirements, your computer still may have difficulty in getting BioShock to run. You can help reduce the strain on your system by turning down the graphics settings within the BioShock main menu before you start the game. Turning the graphics quality down and making sure that the screen resolution matches that of your monitor can be an instant fix. Though the game won't look quite as smooth, it's better than not being able to get into the game at all.
Tablet Users
If you have a digital drawing tablet connected to your computer, it's possible that this entirely unrelated piece of hardware is causing compatibility issues between your computer and BioShock. To fix this problem, open up the Programs and Features menu within your Windows Control Panel. Click on the "Turn Windows Features on or Off" link. Disabling the Tablet PC Optional Components option should fix the problem.