Instructions
Find, download or create a set of soundboard files. There are many pre-built soundboards available online that have been created for easy and quick use. You can also create your own .wav files for use as a soundboard.
Open Ventrillo and select Bindings-->New. Name the binding "TF2 Soundboard" and select "OK."
Create the wave file path by selecting "Add" on the bottom left corner of the bindings dialogue. Select "Wave File" from the audio function window.
Set the key binding for the soundboard by choosing "hotkey" and then pressing the key you want to bind the hotkey to. Be careful not to select a key you already use as a hotkey in TF2. Choose which file you want to bind to the selected key when the "Edit Wave File" window opens.
Save your bindings by clicking "OK." Repeat these steps to bind more soundboard files to your keys. You now have a personal soundboard set to each selected hotkey.