Miscellaneous Cheats
Start with the "Master Code," a special code that must be entered before any other codes will work. If you are using an emulator, however, you can skip this step. The Master Code for "Pokemon Sapphire" is "9266FA6C97BD 905B5ED35F81 B76A68E5FAB1." Once you open the game, you can skip the boring introduction with "B05557898BBD F95340E4DFFD B02FC0E07138 8027CBC08B39." Additionally, throughout the game, you might find yourself paying for the daycare system to train young Pokemon. Enable free daycare with "1DA9FE177458."
Get Around Easier
When traveling around the world, you may run into obstacles or difficult to navigate mazes that prevent you from progressing. Instead of dealing with the frustration, try enabling the "Walk Through Walls" cheat with the code "7881A409 E2026E0C C56CFACA DC167904." In addition to this cheat, you can completely disable random battles with the simple code "32C96211F488," allowing you to walk wherever you want without interruption.
Easy Battles
Close battles can sometimes be lost on a lucky miss. You can avoid this disaster by turning on the "No Misses" cheat. Enter "DF5CCB074CC8 F95E9565CCD8" into your GameShark or emulator to never miss again. Additionally, you might find your Pokemon running low on PP, the resource that powers all of their skills. Gain infinite PP with the "ED59169FCEB6 79BA7465DC00" code. Lastly, if you are still losing, you can completely disable your enemy with the "Always Your Turn" cheat. Simply use "3DC737D7E4BC 3BC67645EE81 D43989B35E7F 9444C92364DE" to deny your enemy the ability to fight back.
Safari Cheats
During "Pokemon Sapphire," you will find yourself in the Hoenn Safari Zone, a Pokemon preserve of sorts which features a variety of wild Pokemon with special requirements to capture them. Instead of battling and subduing the Pokemon like normal, you must use a limited number of special Safari Balls to capture your targets within a strict time limit. Get rid of that time limit with the code "7487A17AED58" and gain infinite Safari Balls with "841ADCEB5C76." If you are getting frustrated with your capture efforts, turn on "Safari Pokemon Easily Caught" with the code "CD70DD2CEB13 7BEBB6D60A2D" to speed things up.