Codes
The options menu of "Marvel Nemesis: Rise of the Imperfects" has a cheats selection that allows the player to enter codes. The codes used in this section actually do not allow the player to make the game easier, but it does automatically unlock cards and comics for the player to view. Entering "THEHAND" will unlock Elektra's swimsuit card. Entering "REIKO" will unlock Solara's swimsuit card. Entering "MONROE" will unlock Storm's swimsuit card. Entering "SAVAGELAND" will unlock every "Fantastic Four" comic included in the game. Entering "NZONE" will unlock every "Tomorrow People" comic in the game.
Unlocked characters and locations
There are two methods in "Marvel Nemesis: Rise of the Imperfects" to unlock characters and locations. The first is to play through the various missions, and with each victory you'll unlock a new character or location. The second and faster way is to play a certain number of one-on-one VS matches. Play VS mode with two players. Beat up the second player and keep selecting rematch. Do this for 10 fights to unlock the Daily Bugle location. Start another VS match at the Daily Bugle. Instead of beating up the second player character, have it run off the edge of the roof to automatically kill the character. Keep selecting rematch. A new character or location will unlock every 10 matches until match 160. This method will unlock every character and location in the game.
AI Cheat
The player can easily win any mission with a "drop" when playing as Spider-Man or any flying character, such as Storm. The AI will always have its character pursue yours during a mission, no matter where you take your character on the screen. Head to the edge of a roof or any place where another character will fall. Hover directly over this drop site using your flying or web-slinging skills. The AI will force all of the enemy characters to chase you, which will cause them to fall to their deaths. The AI will not use flying to protect its character even if the character has flying ability.