Instructions
Point at the monsters with your Wiimote. Once pointed, the game's circular cursor should be on the enemy.
Tap or hold the "Z" button to attack the enemy with paint. Aim for different bits of the enemy's joints, as it will help completely destroy the adversary.
Paint the environment to defeat fight the Jungle bits that are not directly affected by Mickey's paint brush. In the Jungle levels, you can make everything from bananas to televisions fall from their original spaces to fall on the enemy, rendering them defeated.