Instructions
Breed a Wolf and a Moth together by visiting the Laboratory screen and dragging genetic samples from a Wolf and Moth of different genders into the breeding window and click the "Create" button; when the created egg hatches, the offspring will be either a Wolf or a Moth. Breed a genetic sample from this second-generation creature with a genetic sample from another Wolf or Moth, making sure that you don't breed two Wolves or two Moths together to create a third-generation Wolf or Moth. Breed the third-generation Wolf or Moth with another Wolf or Moth, again avoiding a Wolf/Wolf or Moth/Moth pairing; the offspring of this pair will be a Spider.
Breed your Spider with a Fish, creating a second-generation Spider or Fish. Breed this offspring with another Spider or Fish, and continue breeding the offspring in this manner until you've created five generations. Breed the fifth-generation Spider or Fish with another Spider or Fish, avoiding any Spider/Spider or Fish/Fish pairings, and the offspring will be a Calamari.
Breed a Spider with your Calamari, creating another Spider or Calamari. Breed this offspring with another Spider or Calamari as you did with previous combinations, making a total of seven generations of offspring. Breed this seventh-generation Spider or Calamari with a creature of the opposite type to create a Hydra.