Game-clearing Rewards
Beat the game in under five hours on any difficulty to unlock infinite ammo. Beat the game on any difficulty to unlock New Game+, the ability to play as Sheva Alomar, Mercenaries Mode and the "History of Resident Evil" featurette. To unlock the Professional difficulty, beat the game on Veteran difficulty. Beat the game on Amateur to unlock a black-and-white graphics filter, Normal for a sepia filter and Veteran for a grain-effect filter.
Outfits
Beat the game once to unlock Chris's Safari costume and Sheva's Clubbin' costume. Find 25 BSAA emblems to unlock Chris's S.T.A.R.S. outfit and 30 to unlock Sheva's Tribal outfit.
Mercenaries
Earn an A rank on any Mercenaries stage to unlock its corresponding playable character in Mercenaries Mode: Experimental Facility for S.T.A.R.S. Chris, Missile Area for Tribal Sheva, Prison for S.T.A.R.S. Wesker, Ship Deck for Battle Suit Jill, Mines for Midnight Wesker, Village for Safari Chris, Public Assembly for BSAA Jill and Ancient Ruins for Clubbin' Sheva.
PS3 Home
You can earn various "Resident Evil 5" character ornaments to decorate your space in PS3 Home. Simply signing in to Home unlocks Chris Redfield. Beat the game on Normal for Sheva Alomar, Veteran for Jill Valentine and Professional for Wesker.