Things You'll Need
Instructions
Connect the USB cable to the PSP and connect the other end to the computer. The PSP should go into USB mode on its own. Select "USB Connection" on the PSP menu if it doesn't.
Right-click your ISO file on your computer and click "Copy" from the small menu that appears. Click the "Start" button on your computer desktop and click "Computer."
Double-click the "PSP" drive to open its memory stick on your computer. Right-click the "ISO" folder and click "Paste" to transfer the ISO game to the PSP memory stick.
Press the "O" button on the PSP gamepad to disconnect the PSP from the computer. Select the game from the PSP's game section to start playing it.