Things You'll Need
Instructions
Press the "Select" button on your PSP. The visual shell menu, or VSH, will appear. Highlight "USB Mode" using the directional pad on the PSP. Press the "X" button until it says "UMD Drive." Insert the PSP game into the PSP's drive and connect the PSP to the computer with the USB cable.
Right-click the "ISO" file from the window that appears and click "Copy" from the menu that appears. Right-click the computer desktop and click "Copy" to transfer a copy of the game to the computer.
Press the "O" button on the PSP to disconnect the PSP from the computer. Press the "Select" button on the PSP, located underneath the PSP's LCD screen, to bring the VSH menu up again. Highlight "USB Mode" using the directional pad on the PSP. Press the "X" button until it says "Memory Stick." Reconnect the PSP to the computer with the USB cable.
Right-click the "ISO" file on your desktop and click "Copy" from the menu that appears. Right-click the "ISO" folder on the PSP memory stick and click "Paste" to transfer the game backup to the PSP memory stick. Disconnect the PSP from the computer.
Select the game from the PSP menu's game section. The PSP will load the ISO file as if it were a normal PSP game disc. The game will start and you will be able to play the entire game without the CD in the PSP disc drive.