How to Defeat the Game Epic Mickey

Spray the two blisters in the first room, then spray a third blister above the Splashdoosh. Climb the ladder out of this room and spray the blisters as you go.

Spray the big blister on the platform at the top of the ladder to create an opening that you can move through. Avoid the ghosts in the next room and jump onto the platform in the center. Spray the remaining blisters in the room to complete the first bloticle.

Kill as many blotlings as possible from your starting ledge to finish the second bloticle. Collect any health left behind by the blotlings.

Go down the corridor on the right. Stay on the ledges in the next room, eliminate any blisters, and dodge the falling boulders. Return to the main room and the entrance to the third bloticle will automatically appear.

Destroy the blotlings in the main room, then move up to the moving platforms and enter the new passage way. Destroy the blisters and avoid the blotlings here. Take the moving platforms to the next door. Move to the platforms in the next room and spray all the blisters in the room from this vantage point. Go back to the main room.

Eliminate the enemy "sweepers" and explosive "splashdooshes" in the fourth bloticle room. Spray the blisters while avoiding the blotlings and slobbers.